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BPS BPS-Pharmacotherapy Exam Syllabus Topics:

BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

1. A study compared treatment with cinacalcet versus treatment with placebo in subjects with known hyperparathyroidism. The primary outcome of the study was the proportion of study subjects with a mean intact parathyroid hormone level < 250 pg/mL. Among the cinacalcet group (n = 371), 43% of subjects achieved the primary outcome; among the placebo group (n =
370), 5% achieved the primary outcome (p<0.05).
Which of the following is the number needed to treat (NNT)?

A) 1
B) 14
C) 8
D) 3

2. Using a new assay, the following readings for Drug X concentration in a blood sample are obtained: 45 ng/mL, 43 ng/mL, 45 ng/mL, 44 ng/mL, 45 ng/mL, and 45 ng/mL. The true concentration of the drug was reported as 65 ng/mL using the gold-standard assay.
On the basis of these data, the new assay should be characterized in which of the following categories?

A) Accurate but not precise
B) Neither accurate nor precise
C) Both accurate and precise
D) Precise but not accurate

3. A 59-year-old man presents to the neurology clinic with recently diagnosed Parkinson's disease.
At his last visit 2 months ago, selegiline therapy was instituted, and he is tolerating it well. The patient still complains of tremor and rigidity that are interfering with both professional and leisure activities. Which option is most appropriate at this time?

A) Change to carbidopa/levodopa.
B) Change to entacapone.
C) Change to amantadine.
D) Change to ropinirole.

4. A pharmacy resident calculates the appropriate gentamicin dose and frequency for an elderly patient on hemodialysis. This skill reflects what type of residency learning?

A) Evaluation
B) Analysis
C) Comprehension
D) Application

5. Which of the following is an advantage of a crossover-design clinical trial?

A) No randomization needed
B) No carryover effect
C) No period effect
D) Smaller sample size needed

Solutions: